EZSolution™

RNase A is an endoribonuclease that specifically cleaves the single strand RNA at the phosphodiester bond between the 5’-ribose of a nucleotide and the 3’ OH phosphate group of an adjacent pyrimidine...

Biomolecule/Target: N/ASynonyms: Protease K, Endopeptidase K, Tritirachium alkaline proteinaseAlternates names: Protease K, Endopeptidase K, Tritirachium alkaline proteinaseTaglines: A serine...

Biomolecule/Target: N/ASynonyms: Serratia marcescens binuclease; unrestricted endonucleaseAlternates names: Serratia marcescens binuclease; unrestricted endonucleaseTaglines: For digestion of DNA and...

Propidium iodide (PI) is a nuclear and chromosome counterstain commonly used to detect dead cells in a population. PI binds to double-stranded DNA, but it can only cross the plasma membrane of...

A 10 mM (5 mg in 1.34 ml) of the ATP-competitive c-Met kinase inhibitor (Cat. No. B2062) in anhydrous DMSOAlternate Name/Synonyms: PF04217903,...

A 10 mM (5 mg in 888 µl) of the potent inhibitor of FLT kinase, PDGFRβ and c-Kit Tandutinib (Cat. No. 2024) in anhydrous DMSO.Alternate Name/Synonyms: CT53518,...

A 10 mM (5 mg in 1.13 ml) solution of the FLT3 tyrosine kinase inhibitor Crenolanib (Cat. No. 9679) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1.35 ml) of the CDK inhibitor AZD-5438 (Cat. No. B2073) in anhydrous DMSOAlternate Name/Synonyms:...

A 10 mM (1 mg in 306 µl) of the JAK inhibitor Peficitinib (Cat. No. B2474) in anhydrous DMSOAlternate Name/Synonyms: ASP015K, JNJ-54781532,...

A 10 mM (5 mg in 1.55 ml) of the JAK1 inhibitor PF-04965842 (Cat. No. B2470) in anhydrous DMSOAlternate Name/Synonyms:...

A 10 mM (5 mg in 1.28 ml) solution of the potent and selective JAK3 inhibitor Decernotinib (VX-509) in anhydrous DMSO.Alternate Name/Synonyms:...

INF39 is an irreversible and noncytotoxic NLRP3 inhibitor. It inhibits IL-1β release, caspase activation and pyroptosis in THP-1 cells.Alternate Name/Synonyms: INF 39, Ethyl...

A 10 mM (5 mg in 695 µl) of the potent proteasome inhibitor Carfilzomib (Cat. No. 2385) in anhydrous DMSO.Alternate Name/Synonyms: PR-171;...

A 10 mM (5 mg in 1.0 ml) of the potent EGFR inhibitor AZD-9291 (Osimertinib) (Cat. No. 2674) in anhydrous DMSO.Alternate Name/Synonyms: Mereletinib; Osimertinib;...

A 10 mM (5 mg in 941 µl) of the potent MEK inhibitor Cobimetinib (Cat. No. B1689) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1.38 ml) of the potent proteasome inhibitor Ixazomib (Cat. No. B2384) in anhydrous DMSO.Alternate Name/Synonyms: MLN-2238; MLN2238;...

A 10 mM (1 mg in 212 µl) of the potent JAK2/FLT3 inhibitor Pacritinib (SB1518) (Cat. No. 2450) in anhydrous DMSO.Alternate Name/Synonyms: SB-1518, SB1518,...

A 10 mM (5 mg in 1064 µl) solution of the potent JAK2 inhibitor LY-2784544 (Gandotinib) (Cat. No. B1914) in anhydrous DMSO.Alternate Name/Synonyms: LY-2784544,...

A 10 mM (5 mg in 1.12 ml) solution of the potent Syk and JAK inhibitor Cerdulatinib (Cat. No. 2803) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1.18 ml) solution of the potent JAK1 inhibitor Filgotinib (Cat. No. 2871) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1.35 ml) of the JAK1 and JAK2 inhibitor Baricitinib (Cat. No. 2842) in anhydrous DMSO.Alternate Name/Synonyms: INCB028050, LY-3009104, LY 3009104,...

A 10 mM (5 mg in 1.48 ml) solution of the JAK inhibitor PF-03394197 (Oclacitinib) in anhydrous DMSO.Alternate Name/Synonyms: Oclacitinib,...

A 10 mM (5 mg in 1.63 ml) solution of the potent JAK inhibitor Ruxolitinib (Cat. No. 2139) in anhydrous DMSO.Alternate Name/Synonyms: NCB18424;...

A 5 mM ( 1 mg in 520 µl) sterile-filtered solution of the broad spectrum MMP inhibitor GM-6001 (Cat. No. 1799) in anhydrous DMSOAlternate Name/Synonyms:...

A 10 mM (5 mg in 1.67 ml), sterile-filtered solution of the anticancer agent Gemcitabine Hydrochloride (Cat. No. 1759) in deionized waterAlternate Name/Synonyms: Gemcitabine,Gemcitabine,...

A 10 mM (5 mg in 1.47 ml), sterile-filtered solution of the ferroptosis inhibitor Liproxstatin-1 (Cat. No. B2312) in anhydrous DMSOAlternate Name/Synonyms: Liproxstatin-1,...

A 10 mM (5 mg in 703 μl), sterile-filtered solution of the PDX1 inducer BRD-7552 (Cat. No. B2258) in anhydrous DMSO.Alternate Name/Synonyms: Methyl...

A 10 mM (5 mg in 1163 μl), sterile-filtered solution of the cAMP analog, 8-Br-cAMP (Cat. No. 1837) in anhydrous DMSO.Alternate Name/Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic...

A 10 mM (5 mg in 948 μl), sterile-filtered solution of the p38 MAP kinase inhibitor Doramapimod (Cat. No. 1954) in anhydrous DMSO.Alternate Name/Synonyms:...

A 5 mM (2 mg in 963 μl), sterile-filtered solution of the BET bromodomain inhibitor I-BET151 (Cat. No. 2220) in anhydrous DMSO.Alternate Name/Synonyms:...

A 5 mM (2 mg in 1.15 ml), sterile-filtered solution of the BET bromodomain inhibitor PFI-1 (Cat. No. 2203) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1.82 ml), sterile-filtered solution of the phosphodiesterase-4 (PDE4) inhibitor Rolipram (Cat. No. 2010) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1.53 ml), sterile-filtered solution of the Rho Kinase (ROCK) inhibitor Fasudil (Cat. No.1787) in water.Alternate Name/Synonyms: (1-(5-Isoquinolinesulfonyl)homopiperazine,...

A 10 mM (5 mg in 977 μl), sterile-filtered solution of the gamma- secretase inhibitor BMS-299897 (Cat. No. 9606) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1.43 ml), sterile-filtered solution of the RAR agonist TTNPB (Cat. No. 2776) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 2.37 ml), sterile-filtered solution of the STAT3 activation inhibitor Stattic (Cat. No. 2625) in anhydrous DMSO.Alternate Name/Synonyms: 6-​Nitro-​1,​1-​dioxide-​benzo[b]thiophene;...

A 10 mM (5 mg in 2.13 ml), sterile-filtered solution of the neurogenesis promoter (Cat. No. 2563) in anhydrous DMSO.Alternate Name/Synonyms:...

A 5 mM (2.45 mg in 1 ml), sterile-filtered solution of the Smo agonist SAG (Cat. No. 1939) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5.0 mg in 1.50 ml), sterile-filtered solution of the DNA methyltransferase (DNMT) inhibitor RG-108 (Cat. No. 1679) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5.0 mg in 1.50 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer SCR7 Pyrazine (Cat. No. B1119) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5.0 mg in 954 μl), sterile-filtered solution of the HDR (homology-directed repair) enhancer RS-1 (Cat. No. B1118) in anhydrous DMSO.Alternate Name/Synonyms:...

A 5 mM (5.0 mg in 2.42 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer NU-7441 (Cat. No. B1117) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5.0 mg in 1.66 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer Nocodazole (Cat. No. 2185) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5.0 mg in 855 μl), sterile-filtered solution of the HDR (homology-directed repair) enhancer L-755,507 (Cat. No. B1116) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5.0 mg in 1.78 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer Brefeldin A (Cat. No. 1560) in anhydrous DMSO.Alternate Name/Synonyms: Ascotoxin, BFA, Cyanein,...

A 10 mM (5.06 mg in 1 ml) solution of the neuroprotective agent P7C3-A20 (Cat. No. 2850) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 162 μl) solution of the p53-MDM2 interaction inhibitor RG7388 (Cat. No. 2577) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (10 mg in 3.86 ml) solution of the antitumor and anti-inflammatory agent (R, S)-Lenalidomide (Cat. No. 1862) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 183 μl) of the antitumor agent Erastin (Cat. No. 2231) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (10 mg in 2.17 ml), sterile-filtered solution of the necroptosis inhibitor Necrosulfonamide (Cat. No. 9635) in anhydrous DMSO.Alternate Name/Synonyms:...

EZSolution(TM) Triacsicn C, is an Inhibitor of acyl-CoA synthetase (IC₅₀ = 6.3 μM in Raji cells). Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer...

A 10 mM (5 mg in 1294 µl) of the rapid apoptosis inducer Raptinal (Cat. No. 9626) in anhydrous DMSO.Alternate Name/Synonyms: 9H, 9’H-[9,9’-bifluorene]-9,9’-dicarbaldehydeAppearance: LiquidAppearance:...

A 10 mM (5 mg in 1807 µl) of PPARγ antagonist GW9662 (Cat. No. 1697) in anhydrous DMSO.Alternate Name/Synonyms: 2-Chloro-5-nitrobenzanilideAppearance: LiquidAppearance: A 10 mM solution in...

A 10 mM (5 mg in 1403 µl) of PPARγ agonist Pioglitazone (Cat. No. 1877) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 2270 µl) of the JNK inhibitor SP600125 (Cat. No.1669) in anhydrous DMSO.Alternate Name/Synonyms: Anthra[1-9-cd]pyrazol-6(2H)-oneAppearance: LiquidAppearance: 11 mM solution in...

A 10 mM (1 mg in 226 µl) of PKC inhibitor Gö 6983 (Cat. No.9539) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 171 µl) of Hsp90 inhibitor 17-AAG (Cat. No.1774) in anhydrous DMSO.Alternate Name/Synonyms: Telatinib; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)geldanamycin;...

A 10 mM (1 mg in 264 µl) of potent Wnt signaling pathway inhibitor (Cat. No. 2063) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 2098 µl) of the VEGFR kinase inhibitor SU-5416 (Cat. No. 9491) in anhydrous DMSO.Alternate Name/Synonyms: 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one;...

A 10 mM (5 mg in 1456 µl) of the ALK5 inhibitor SB-525334 (Cat. No. 2880) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (10 mg in 1080 µl) of the EGFR inhibitor Lapatinib ditosylate (Cat. No.1624) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1038 µl) of the HMG-CoA inhibitor Rosuvastatin (Cat. No. 1955) in anhydrous DMSO.Alternate Name/Synonyms:...

5-Fluoroorotic Acid (5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) decarboxylase. 5-FOA is toxic to yeast cells that...

DAF-2 diacetate is a cell-permeable derivative of DAF-2 (Cat. No. 2752) and a very useful indicator of nitric oxide (NO). Upon entry into the cell, DAF-2 diacetate is converted into the less...

DAF-2 is a highly sensitive fluorescent indicator commonly used for the detection of nitric oxide (NO). It reacts with NO in the presence of oxygen to yield the highly fluorescent triazolofluorescein...

A 10 mM (5 mg in 1218 µl) solution of adenylyl cyclase activator Forskolin (Cat. No. 1531) in anhydrous DMSO.Alternate Name/Synonyms: Coleonol, Colforsin,...

A 10 mM (5 mg in 1019 µl) solution of the HMTase inhibitor BIX01294 (Cat. No. 1678) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 233 µl) of the stem cell fate modulator StemRegenin 1 (Cat. No. 2642) in anhydrous DMSOAlternate Name/Synonyms:...

A 10 mM (5 mg in 1740 µl) of the ALK5 inhibitor RepSox (Cat. No. 1894) in anhydrous DMSO.Alternate Name/Synonyms: 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E-616452Appearance:...

A 10 mM (1 mg in 231 µl) of the ROCK inhibitor GSK429286A (Cat. No. 2637) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 206 µl) of the GSK-3 inhibitor CHIR-98014 (Cat. No. 2595) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1744 µl) of the PDK1 activator PS48 (Cat. No. 1869) in anhydrous DMSO.Alternate Name/Synonyms: (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic acidAppearance: LiquidAppearance: A 10 mM...

A small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits...

Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1, <4 nM for mSCD1). Also exhibited in vivo efficacy with dose-dependent...

Cell-permeable. A potent, selective , reversible and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM in the presence of 5 µM ATP and no AMP). Does not affect the...

A potent, cell-permeable JAK2 inhibitor. A novel analog of the JAK2 inhibitor AG490 (Cat. No. 1570-5) that blocks STAT3 and phosphoinositide-3-kinase pathways. It is significantly more potent and...

A cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 0.5 nM). Inhibits neutral cysteine proteases and the proteasome (Ki =...

Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the...

Potent, broad spectrum matrix metalloprotease (MMP) inhibitor (IC₅₀ values are 3, 4, 4, 6 and 20 nM for MMP -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and...

A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes...

A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (Cat. No. 1864) (EC₅₀ = 210 nM versus EC₅₀ = 490 nM), as well as showing no nonspecific...

Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor (IC₅₀ = 37 nM). It raises high-density lipoprotein (HDL) cholesterol and reduces low-density lipoprotein (LDL) cholesterol levels...

Dalcetrapib is a potent CETP modulator. It is a thioester pro-drug that is rapidly hydrolyzed to generate a pharmacologically active thiol. Dalcetrapib modulates cholesteryl ester transfer protein...

Anacetrapib is a potent inhibitor of the cholesteryl ester transfer protein (CETP)-dependent transfer of cholesteryl ester (CE) (IC₅₀ = 17 ± 4.8 nM); it significantly raises HDL cholesterol levels in...

Supplied as a 100X concentrated sterile-filtered solution. Pencillin/Streptomycin/Amphotericin B contains 10,000 IU/ml of Penicillin potassium (Cat. No. 2504), 10 mg/ml of Streptomycin sulfate (Cat...

Supplied as a 100X concentrated sterile-filtered solution. Pencillin-Streptomycin (Pen/Strep) is an antibacterial solution comprised of Penicillin (10,000 units/ml), a β-lactam, and Streptomycin (10...

A solution (34 mg/ml, 0.2 µM sterile filtered) of Chloramphenicol (Cat. No. 2486) in 100% Ethanol. Suitable for cell culture applications.Alternate Name/Synonyms:...

Ampicillin sodium is a β-lactam antibiotic structurally related to penicillin. Inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell...

A 10 mM (5 mg in 874 µl) solution of the of the EZH2 inhibitor EPZ6438 (Cat. No.2383) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 178 µl) solution of the of DOT1L methyltransferase inhibitor EPZ5676 (Cat. No. 2382) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (2 mg in 370 µl) solution of the EZH2 inhibitor EPZ-005687 (Cat. No. 2364) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 190 µl) solution of the EZH2 inhibitor GSK126 (Cat. No. 2282) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 185 µl) solution of the EZH2 inhibitor GSK343 (Cat. No. 2281) in anhydrous DMSO.Alternate Name/Synonyms:...

A potent, selective and ATP-competitive mTOR inhibitor (IC₅₀ = 2.1 nM for mTORC1). Torin 2 displays 800-fold selectivity for mTOR over PI3K (cellular EC₅₀ values of 0.25 nM and 200 nM, respectively)...

A potent, selective and ATP-competitive mTOR inhibitor, with IC₅₀ values of 2 and 10 nM for mTORC1 and mTORC2 respectively; Torin1 displays 1000-fold selectivity for mTOR over PI3K (EC₅₀ = 1800 nM)...

A cell- permeable activator of AMP-activated protein kinase (AMPK), a metabolic sensor involved in both cellular and whole body energy homeostasis. In vivo, pharmacologic activation of AMPK with...

A 10 mM (1 mg in 330 µl) of Trichostatin A (Cat. No. 1606-1) in anhydrous DMSO.Alternate Name/Synonyms: TSA,...

A 10 mM (1 mg in 260 µl) solution of the proteasome inhibitor PS-341 (Cat. No. 1846) in anhydrous DMSO.Alternate Name/Synonyms: MG-341;...

A 10 mM (1 mg in 217 µl) solution of the proteasome inhibitor MG-115 (Cat. No. 1831) in anhydrous DMSO.Alternate Name/Synonyms: Z-LL-NVa-CHO; Z-Leu-Leu-Nva-CHO; MG115Appearance: LiquidAppearance:...

A 10 mM (1 mg in 219 µl) solution of the Bromodomain inhibitor (+)-JQ1 (Cat. No. 2070-1) in anhydrous DMSO.Alternate Name/Synonyms:...