EZSolution™

Luciferin is a substrate for luciferase. It is oxidised by luciferase to generate light in the presence of ATP. Luciferase is used as a reporter gene linked to a promoter of interest. Luciferin is used to assess the expression of the luciferase gene. It...

A 10 mM (5 mg in 922 µl) solution of the dual inhibitor of the tyrosine kinases c-Src and Abl Saracatinib (AZD-0530) (Cat. No. 1582) in anhydrous DMSO.Alternate Name/Synonyms: AZD0530,...

A 10 mM (5 mg in 953 µl) of the potent JAK2 inhibitor TG101348 (Fedratinib) in anhydrous DMSO.Alternate Name/Synonyms: N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide; Fedratinib; TG101348;...

A 10 mM (5 mg in 1067 μl), sterile-filtered solution of the CBP/EP300 bromodomain inhibitor I-CBP112 (Cat. No. 9405) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1236 μl), sterile-filtered solution of the bromodomain inhibitor Bromosporine (Cat. No. 2652) in anhydrous DMSO.Alternate Name/Synonyms: Ethyl...

A solution (20 mg/ml) of the antibiotic Phleomycin (Cat. No. 2724) in deionized water. Sterile-filtered.Alternate Name/Synonyms:...

A 10 mM (1 mg in 166 µl) of heme-independent soluble guanylyl cyclase activator BAY 58-2667 hydrochloride (Cat. No. 2027) in anhydrous DMSO.Alternate Name/Synonyms: 4-((4-carboxybutyl)(2-((4-phenethylbenzol)- oxy)phenethyl)amino)methyl(benzoic) acid;...

A 10 mM (5 mg in 1653 µl) of the PARP inhibitor DPQ (Cat. No. 1899) in anhydrous DMSO.Alternate Name/Synonyms: 3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinoneAppearance: LiquidAppearance: A 10 mM solution in anhydrous DMSOAppearance:...

Inhibitor of TNF-α processing (IC₅₀ = 100 nM), similar to TAPI-0 (Cat. No. 2067-1), but more stable in tissue culture and in vivo. Inhibits TACE and other metalloproteases. Blocks release of TNF- α (IC₅₀ = 50-100 μM), APP (1-8 μM), IL6R (5- 10 μM), TNFRI...

A 10 mM (1 mg in 381 µl) solution of the EZH2 inhibitor 3-Deazaneplanocin (Cat. No. 2060) in anhydrous DMSO.Alternate Name/Synonyms: DZNep; NSC 617989;...

A 10 mM (3.20 mg in 1 ml) solution of the ROCK inhibitor Y-27632, Dihydrochloride (Cat. No. 1596) in deionized water.Alternate Name/Synonyms: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecar boxamide dihydrochlorideAppearance: LiquidAppearance: A...

A 10 mM (4.65 mg in 1 ml), sterile-filtered solution of the GSK-3β inhibitor CHIR99021 (Cat. No. 1677) in anhydrous DMSO.Alternate Name/Synonyms:...