Human CellExp™ Akt1 Protein (His Tagged & Strep Tagged), human recombinant

Biomolecule/Target: Akt1

Synonyms: RAC-alpha serine/threonine-protein kinase, AKT1, PKB, RAC, RAC-PK-alpha, PKB alpha, Proto-oncogene cAkt

Alternates names: RAC-alpha serine/threonine-protein kinase, AKT1, PKB, RAC, RAC-PK-alpha, PKB alpha, Proto-oncogene cAkt

Taglines: One of 3 serine/threonine-protein kinases that regulate many process including metabolism, proliferation, cell survival, growth and angiogenesis.

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 207

NCBI Gene Symbol: AKT1

Gene Source: Human

Accession #: P31749

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGE #: >92%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 60 kDa

Concentration: N/A

Appearance: Dry powder

Physical form description: Lyophilized powder

Reconstitution Instructions: Reconstitute in sterile deionized water to a stock solution of 200 µg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage.

Background Information: AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. AKT regulates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', resulting in inhibition of its kinase activity.

Amino acid sequence: Met 1 - Ala 480

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans