Biovision
Human CellExp™ MMP-3, Human Recombinant
- SKU:
- 26-P1310
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 10 µg
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: MMP-3
Synonyms: Stromelysin-1, EC 3.4.24.17, Matrix metalloproteinase-3, MMP-3, Transin-1, SL-1, STMY, STR1, STMY1, MGC126102, MGC126103, MGC126104
Alternates names: Stromelysin-1, EC 3.4.24.17, Matrix metalloproteinase-3, MMP-3, Transin-1, SL-1, STMY, STR1, STMY1, MGC126102, MGC126103, MGC126104
Taglines: A Protein involved in breakdown of extracellular matrix
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 4314
NCBI Gene Symbol: MMP3
Gene Source: Human
Accession #: P08254
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGE #: ≥95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 52 kDa
Concentration: N/A
Appearance: Liquid
Physical form description: In 20mM Tris-HCl, 150mM NaCl and 0.05% Brij35, pH 7.5
Reconstitution Instructions: N/A
Background Information: MMP-3 enzyme is also known as Stromelysin-1or as Transin-1 which hydrolyzes natural collagen at physiological pH and temperature. It dissolves the intervertebral nucleus pulposus and annulus fibrosus of Herniated Lumbar Intervertebral Disk . MMP-3 hydrolyzes components of the extracellular matrix like proteoglycan, laminin, fibronectin, gelatin and collagen types III, IV and IX. It also activates pro-MMP-9 and pro-MMP-8 and superactivates plasmin activated MMP-1. MMP-3 is secreted as a latent proenzyme and is activated by a variety of proteinases, e.g. plasmin, trypsin, chymotrypsin, cathepsin G or human neutrophil elastase. MMP-3 was found to be capable of activating the precursor of IL1-beta.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans