Biovision
BioSim™ Rituximab (Human) ELISA Kit
- SKU:
- 26-E4371
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 100 Assays
- Storage Conditions:
- 4°C
- Shipping Conditions:
- Gel Pack
- Shelf life:
- 12 months
Description
Rituximab is a genetically engineered chimeric murine/human monoclonal antibody specific to CD20. CD20 is an approximately 35 kDa transmembrane phosphoprotein involved in the activation, proliferation, and differentiation of B-lymphocytes. It is absent in terminally differentiated plasma cells. The Fab domain of rituximab binds to the CD20 antigen on B-lymphocytes and the Fc domain recruits immune effector functions to induce apoptosis in B cells and is used in the treatment of leukemias and lymphomas, some autoimmune disorders, and organ transplant. BioVision’s BioSim™ Rituximab ELISA kit is designed to quantify/measure the Rituximab with high specificity and sensitivity in biological matrices.
Alternate Name: B1, S7, Bp35, CD20, CVID5, MS4A2, LEU-16, MS4A1, CAS 174722-31-7
Tag Line: A Sandwich ELISA kit for the quantitative measurement of Rituximab in human serum or plasma.
Summary: N/A
Detection Method: Absorbance (450 nm)
Sample Type: Human serum and plasma
Species Reactivity: Human
Applications: This ELISA kit is used for quantitative measurement of Rituximab in human serum and plasma
Features & Benefits: Recovery rate: < 100 ± 30% with normal human serum samples with known concentrations Assay Precision: Intra-Assay: CV < 30%; Inter-Assay: CV < 30% (CV (%) = SD/mean X 100) Cross Reactivity: No significant cross-reactivity or interference with other proteins present in native human serum or other therapeutic immunoglobulins. Easy, convenient, sensitive and time-saving method to measure the level of Rituximab in human serum and plasma. Detection Range: 3 - 300 ng/ml Sensitivity: 3 ng/ml