Anti-TIMP2 recMAb™ Antibody

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Antibody Target: TIMP2

Target Alternative Name: DDC8, CSC-21K, Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue Inhibitor of Metalloproteinase 2

Tag Line: Recombinant mouse monoclonal antibody to detect TIMP2 expression in human, mouse, rat, rabbit, guinea pig, cow and zebrafish samples

Category: Primary antibody

Host: Mouse

Antibody Type: Monoclonal

Isotype: IgG1, kappa

Clone#: rTIMP2/2335

Species Reactivities: Zebrafish,Guinea pig,Bovine,Rat,Rabbit,Mouse,Human

Immunogen Sequence: Synthetic peptide targeting residues around aa 40-70 at the N-terminus of human TIMP2

Accession #: P16035

Gene Id: 7077

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In 10 mM PBS

Purification: Protein A/G purified

Application: Immunohistochemistry (IHC)

Positive Control: N/A

Application And Usages: IHC (1-2 µg/ml)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE