recMAb™ Anti-LOXL2 Antibody

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Antibody Target: LOXL2

Target Alternative Name: LOR, LOR2, WS9-14, LOXL2, EC 1.4.3.13, EC 1.4.3

Tag Line: Recombinant rabbit monoclonal antibody to detect the expression of LOXL2 in human, mouse, and rat samples

Category: Primary antibody

Host: Rabbit

Antibody Type: Monoclonal

Isotype: IgG

Clone#: 2E5

Species Reactivities: Rat,Mouse,Human

Immunogen Sequence: Synthetic peptide derived from human LOXL2

Accession #: Q9Y4K0

Gene Id: 4017

Appearance: Colorless liquid

Form: Liquid

Concentration: N/A

Formulation: In PBS, pH 7.4, 150 mM NaCl, 50% glycerol, 0.02% sodium azide

Purification: Affinity purified

Application: Immunohistochemistry (IHC),Immunofluorescence (IF),Western Blotting,Flow Cytometry

Positive Control: N/A

Application And Usages: WB 1:500-1:5000, IHC 1:50-1:200, IF 1:20-1:200, FC 1:20-1:200

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: TRUE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: TRUE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: TRUE