Biovision
recMAb™ Anti-MYH11 Antibody
- SKU:
- 26-A2210
- UPC:
- MPN:
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 100 µg
- Storage Condition:
- -20ºC
- Shipping Condition:
- Gel Pack
- Shelf Life:
- 12 months
Description
The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Antibody Target: MYH11
Target Alternative Name: AAT4, FAA4, SMHC, SMMHC, KIAA0866, Smooth muscle myosin heavy chain 11, SM1, SM2
Tag Line: Recombinant rabbit monoclonal antibody to detect MyoD1 expression in human samples
Category: Primary antibody
Host: Rabbit
Antibody Type: Monoclonal
Isotype: IgG
Clone#: MYH11/2303R
Species Reactivities: Bovine,Rabbit,Porcine,Guinea Pig,Cat,Dog,Rat,Chicken,Human
Immunogen Sequence: Recombinant full-length human MYH11 protein
Accession #: P35749
Gene Id: 4329
Appearance: Colorless liquid
Form: Liquid
Concentration: 1 mg/ml
Formulation: In 10 mM PBS
Purification: Protein A/G purified
Application: Immunohistochemistry (IHC)
Positive Control: N/A
Application And Usages: IHC (1-2 µg/ml)
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
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