EZSolution™ABT-494 (Upadacitinib)

A 10 mM (5 mg in 1.31 ml) solution of the potent JAK1 inhibitor ABT-494 (Upadacitinib) in anhydrous DMSO.

Alternate Name/Synonyms: (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide; Upadacitinib; ABT-494; ABT494

Appearance: Liquid

Appearance: A 10 mM solution in anhydrous DMSO

Appearance: 1310726-60-3

Appearance: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₉F₃N₆O

Molecular Weight: 380.37

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent and selective Janus kinase JAK-1 inhibitor

MDL Number:

PubChem CID: 58557659

SMILES: CCC1CN(CC1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F

InChi: InChI=1S/C17H19F3N6O/c1-2-10-7-25(16(27)24-9-17(18,19)20)8-11(10)13-5-22-14-6-23-15-12(26(13)14)3-4-21-15/h3-6,10-11,21H,2,7-9H2,1H3,(H,24,27)/t10-,11+/m1/s1

InChi Key: WYQFJHHDOKWSHR-MNOVXSKESA-N

Category: Biochemicals