Biovision
EZSolution™ AICAR
- SKU:
- 26-2344
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 50 mg
- Storage Condition:
- -20 ̊C
- Shipping Condition:
- gel pack
- Shelf Life:
- 12 months
Description
A cell- permeable activator of AMP-activated protein kinase (AMPK), a metabolic sensor involved in both cellular and whole body energy homeostasis. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle. AICAR is able to activate the molecular circuitry of pluripotency in mESC and to induce the expression of several key regulators of pluripotency in somatic cells.
Alternate Name/Synonyms: N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide
Appearance: Liquid
Appearance: A 250 mM solution in D.I. water
Appearance: 2627-69-2
Appearance: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₉H₁₄N₄O₅
Molecular Weight: 258.23
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: N/A
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An AMPK activator
MDL Number: MFCD00869751
PubChem CID: 17513
SMILES: C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N
InChi: InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
InChi Key: RTRQQBHATOEIAF-UUOKFMHZSA-N
Category: Biochemicals