EZSolution™ AICAR

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SKU:
26-2344
Availability:
Usually Shipped in 5 Working Days
Size:
50 mg
Storage Condition:
-20 ̊C
Shipping Condition:
gel pack
Shelf Life:
12 months
£167.70
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Description

A cell- permeable activator of AMP-activated protein kinase (AMPK), a metabolic sensor involved in both cellular and whole body energy homeostasis. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle. AICAR is able to activate the molecular circuitry of pluripotency in mESC and to induce the expression of several key regulators of pluripotency in somatic cells.

Alternate Name/Synonyms: N1-(β-D-Ribofuranosyl)-5-aminoimidaz­ole-4-carboxamide

Appearance: Liquid

Appearance: A 250 mM solution in D.I. water

Appearance: 2627-69-2

Appearance: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₉H₁₄N₄O₅

Molecular Weight: 258.23

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An AMPK activator

MDL Number: MFCD00869751

PubChem CID: 17513

SMILES: C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N

InChi: InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1

InChi Key: RTRQQBHATOEIAF-UUOKFMHZSA-N

Category: Biochemicals

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