EZSolution™ EPZ-5676

A 10 mM (1 mg in 178 µl) solution of the of DOT1L methyltransferase inhibitor EPZ5676 (Cat. No. 2382) in anhydrous DMSO.

Alternate Name/Synonyms: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol

Appearance: Liquid

Appearance: 10 mM solution in DMSO

Appearance: 1380288-87-8

Appearance: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₀H₄₂N₈O₃

Molecular Weight: 562.71

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A potent DOT1L inhibitor

MDL Number: N/A

PubChem CID: N/A

SMILES: CC(C)(C)C1=CC2=C(NC(CC[C@H]3C[C@@H](N(C[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C(N=CN=C6C6N)=C6N=C5)O4)C(C)C)C3)=N2)C=C1

InChi: InChI=1S/C30H42N8O3/c1-16(2)37(13-22-25(39)26(40)29(41-22)38-15-34-24-27(31)32-14-33-28(24)38)19-10-17(11-19)6-9-23-35-20-8-7-18(30(3,4)5)12-21(20)36-23/h7-8,12,14-17,19,22,25-26,29,39-40H,6,9-11,13H2,1-5H3,(H,35,36)(H2,31,32,33)/t17-,19+,22-,25-,26-,29-/m1/s1

InChi Key: LXFOLMYKSYSZQS-LURJZOHASA-N

Category: Biochemicals