Human CellExp™ FGF-7 (KGF), Human Recombinant

Biomolecule/Target: N/A

Synonyms: Human Cellexp Human Recombinant FGF-7 (KGF)

Alternates names: HBGF-7, FGF7, FGF-7, KGF

Taglines: A potent mitogen for keratinocytes and epithelial cells

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 2252

NCBI Gene Symbol: FGF7

Gene Source: Human

Accession #: P21781

Recombinant: Yes

Source: Human cell expressed

Purity by SDS-PAGE #: ≥95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 μg of protein

Activity (Specifications/test method): N/A

Biological activity: ED₅₀ is typically 1.5 to 7.5 ng/mL. The specific activity was determined by the Dose-dependent stimulation of the proliferation of 4MBr-5 cells (monkey epithelial cell line).

Results: 1.5 to 7.5 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 17 and 30 kDa, monomer, glycosylated

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from a PBS solution.

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Background Information: FGF-7 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans