Human CellExp™ MMP-13, Human Recombinant

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Usually Shipped in 5 Working Days
10 µg
Storage Temperature:
Shipping Conditions:
Gel Pack
Shelf Life:
9 months
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Biomolecule/Target: N/A

Synonyms: Collagenase 3, Matrix metalloproteinase-13, CLG 3, CLG3EC, EC

Alternates names: Collagenase 3, Matrix metalloproteinase-13, CLG 3, CLG3EC, EC

Taglines: A Protein involved in breakdown of extracellular matrix

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 4322

NCBI Gene Symbol: MMP13

Gene Source: Human

Accession #: P45452

Recombinant: TRUE

Source: HEK 293 cells

Purity by SDS-PAGE #: >95%

Assay: SDS - PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 53 kDa (6xHis tag at the C-terminus)

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.

Background Information: MMP13 or collagenase 3 is an endopeptidase that is part of the calcium and zinc dependent matrix metalloproteinase family. Like most MMPs, it is secreted as an inactive pro-form and is activated once its pro-domain is cleaved. Additionally, MMP13 is expressed by fibroblasts, chondrocytes, and squamous epithelial cells. MMP-13 (Collagenase-3) has been demonstrated to degrade a range of extracellular matrix proteins, including collagen types I, II, III, IV, IX, X and XIV, gelatin, aggrecan, perlecan and fibronectin. Furthermore, it is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.

Amino acid sequence: Leu 20 – Cys 471

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans

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