Human CellExp™ SARS-CoV-2 Nucleoprotein, Recombinant

Biomolecule/Target: N/A

Synonyms: Nucleoprotein, Nucleocapsid protein, NC, N, NP, NC_045512.2, GU280_gp10, Gene ID: 43740575, YP_009724397.2, ORF9 structural protein, nucleocapsid phosphoprotein

Alternates names: Nucleoprotein, Nucleocapsid protein, NC, N, NP, NC_045512.2, GU280_gp10, Gene ID: 43740575, YP_009724397.2, ORF9 structural protein, nucleocapsid phosphoprotein

Taglines: Plays a role in viral assembly and subgenomic viral RNA transcription and replication

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 43740575

NCBI Gene Symbol: NP

Gene Source: Coronavirus

Accession #: YP_009724397.2

Recombinant: TRUE

Source: HEK 293 cells

Purity by SDS-PAGE #: >95%

Assay: SDS - PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 46 kDa (6xHis tag at the C-terminus)

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Lyophilized

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex

Background Information: Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus called SARS-associated coronavirus (SARS-CoV). Novel Coronavirus (COVID-19) is caused by SARS-CoV-2. SARS coronavirus belongs to a family of enveloped coronaviruses. Coronaviruses are enveloped, single-stranded, positive-sense RNA viruses that belong to the subfamily Coronavirinae. The coronavirus genome encodes a spike protein (S), an envelope protein, a membrane protein, and a nucleoprotein in this order. Nucleoprotein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. It also plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.

Amino acid sequence: Ser 2 – Ala 419

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans