Biovision
Human CellExp™ SARS-CoV-2 S1 Protein (D614G), Recombinant
- SKU:
- 26-P1652
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20ºC
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: N/A
Synonyms: SARS-CoV-2 S1 Protein (D614G), Recombinant,SARS-CoV-2 S1 Protein (D614G),SARS-CoV-2 S1 (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G), Recombinant,S1 Protein (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G),Human CellExp™ SARS-CoV-2 S1 Protein (D614G),S1 (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G)
Alternates names: SARS-CoV-2 S1 Protein (D614G), Recombinant,SARS-CoV-2 S1 Protein (D614G),SARS-CoV-2 S1 (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G), Recombinant,S1 Protein (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G),Human CellExp™ SARS-CoV-2 S1 Protein (D614G),S1 (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G)
Taglines: Recombinant SARS-CoV-2 S1 spike protein with a mutation (D614G)
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: N/A
NCBI Gene Symbol: N/A
Gene Source: Recombinant
Accession #: N/A
Recombinant: TRUE
Source: HEK 293 cells
Purity by SDS-PAGE #: > 95% SDS-PAGE
Assay: N/A
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 120 kDa
Concentration: Lot dependent
Appearance: Lyophilized powder
Physical form description: N/A
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.
Background Information: SARS-CoV-2, the causative virus of COVID-19, uses the viral Spike (S) protein for host cell attachment and entry. The virus uses multiple factors including the human protease Furin, Angiotensin converting enzyme 2 (ACE2), Neuropilin-1 (NRP1) and the transmembrane protease serine 2 (TMPRSS2) for receptor interactions. The S protein has two domains S1 and S2, where S1 facilitates initial binding to the receptor and the S2 domain drives the membrane fusion and eventual entry of the virus. The S glycoprotein serves as an important target for monoclonal antibodies, entry inhibitors, and vaccines. Within the S1 protein, the conserved receptor-binding domain (RBD) binds with a high affinity for ACE2. Recently, a new strain of SARS-CoV-2 has been discovered with a mutation in the S1 protein (amino acid D614 to G614) outside the RBD. Early studies provide evidence that D614G SARS-CoV-2 virus strain is likely to be more infectious and is present in the majority of current infections globally.
Amino acid sequence: Val 16 - Arg 685
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans