CaspGLOW™ Green Active Caspase-3/7 Staining Kit

Activation of caspases plays a central role in apoptosis. The CaspGLOW™ Green Active Caspase-3/7 Staining Kit provides a convenient means for detecting activated caspase-3/7 in living cells. The assay utilizes the caspase inhibitor DEVD-FMK conjugated to FITC (Green-DEVD-FMK) as the fluorescent in situ marker. Green-DEVD-FMK is cell permeable, nontoxic, and irreversibly binds to the activated caspase-3/7 in apoptotic cells. The green fluorescence label allows the direct detection of activated caspase-3/7 in apoptotic cells by fluorescence microscopy, flow cytometry, or fluorescence plate reader. The caspase inhibitor, Z-VAD-FMK, is included in the kit as an additional control. It can be used to inhibit caspase activation in an induced culture.

Alternate Name: Caspase-3/7 Staining, Active Caspase-3/7 Staining Kit, CaspGLOW™ Caspase-3/7 Staining, Caspase, Green Active Caspase-3/7 Staining Kit, CaspGLOW™ Green Active Caspase-3/7 Staining Kit, CaspGLOW™, Caspase Staining Kit, CaspGLOW™ Active Caspase-3/7 Staining Kit, CaspGLOW, CaspGLOW™ Caspase-3/7 Staining Kit, CaspGLOW™ Caspase Staining Kit, Caspase-3/7 Staining Kit, Green Active Caspase-3/7 Staining Kit, CaspGLOW™ Green Active Caspase-3/7 Kit

Tag Line: For detection of activated caspase-3/7 in apoptotic cells

Summary: Activation of caspases plays a central role in apoptosis. The CaspGLOW™ Green Active Caspase-3/7 Staining Kit provides a convenient means for detecting activated caspase-3/7 in living cells. The assay utilizes the caspase inhibitor DEVD-FMK conjugated to FITC (Green-DEVD-FMK) as the fluorescent in situ marker. Green-DEVD-FMK is cell permeable, nontoxic, and irreversibly binds to the activated caspase-3/7 in apoptotic cells. The green fluorescence label allows the direct detection of activated caspase-3/7 in apoptotic cells by fluorescence microscopy, flow cytometry, or fluorescence plate reader. The caspase inhibitor, Z-VAD-FMK, is included in the kit as an additional control. It can be used to inhibit caspase activation in an induced culture.

Detection Method: Fluorescence microscopy, flow cytometry, or fluorescence plate reader.

Sample Type: Living cells

Species Reactivity: Mammalian

Applications: For detecting activated caspase-3/7 in living cells

Features & Benefits: The caspase inhibitor, Z-VAD-FMK, is included in the kit as an additional control, The green fluorescence label allows for direct detection of activated caspases in living cells, Fast and convenient