QuickDetect™ Proinsulin (Human) ELISA Kit

Proinsulin is synthesized in the beta cells of the pancreas and is the precursor molecule for insulin. Most proinsulin is converted to insulin and C-Peptide, which are secreted in equimolar amounts into the blood. About 15% is not converted and is released as proinsulin. The biological activity of proinsulin is only about 10% of Insulin, but the half-life of proinsulin is three times as long as insulin. The level of proinsulin in serum can be a reflection of ß cell status. Both IDDM and NIDDM are characterized by dysfunction of the pancreatic beta cells. Elevated proinsulin levels have been noted at the onset of IDDM and in healthy siblings of IDDM patients. Proinsulin levels may also be increased in patients with established NIDDM. BioVision’s QuickDetect™ Proinsulin ELISA kit is a sandwich ELISA assay for measuring the quantity of human Proinsulin in serum, plasma and cell culture and other biological fluid. The entire process can be performed within 90 minutes with only a single incubation and a wash step respectively, resulting in fewer handling steps, fewer errors and more consistent results.

Alternate Name: N/A

Tag Line: A rapid sandwich ELISA kit for the quantitative measurement of Proinsulin in human serum, plasma, cell culture supernatnat and other biological fluids

Summary: • Detection method- Absorbance (450 nm)• Species reactivity- Human• Application- quantitative measurement of Proinsulin in human serum, plasma, cell culture supernatant, and other biological fluid.

Detection Method: Absorbance (450 nm)

Sample Type: Human serum, plasma, tissue homogenates and other biological fluids.

Species Reactivity: Human

Applications: This ELISA kit is used for quantitative measurement of Proinsulin in human serum, plasma, cell culture supernatant and other biological fluids.

Features & Benefits: Easy, convenient and time-saving method to measure the level of Proinsulin in human serum, plasma, culture supernatants and other biological fluids.The entire assay can be performed within 90 minutes with only a single incubation and a wash step respectively, resulting in fewer handling steps, fewer errors and more consistent results.Detection Range: 15.6 – 1000 pg/ml