BioSim™ Adalimumab (Human) ELISA Kit

Adalimumab (Humira®) is a recombinant human IgG1 monoclonal antibody specific for Tumor Necrosis Factor-Alpha (TNF-α) and is used to treat rheumatic arthritis, intestinal disorders, dermatological diseases and cancer. Adalimumab specifically binds to TNF alpha and blocks its interaction with p55 and p75 cell surface TNF receptors and reduces the inflammation and subsequently improves the patient’s health. Drug level quantification can be important to adapt patient prescription or to switch to an alternative TNF inhibitor drug.This Adalimumab ELISA kit has been developed for specific quantification of Adalimumab concentration in human serum or plasma with high sensitivity and reproducibility. BioVision’s BioSim™ Adalimumab ELISA kit is a sandwich ELISA assay for the quantitative measurement of Adalimumab in human serum, plasma. The density of color is proportional to the amount of human Adalimumab captured from the samples.

Alternate Name: DIF, TNFA, TNFSF2, TNLG1F, TNF-alpha, TNF, CAS 331731-18-1

Tag Line: A Sandwich ELISA kit for the quantitative measurement of Adalimumab in human serum or plasma.

Summary: N/A

Detection Method: Absorbance (450 nm)

Sample Type: Human serum and plasma

Species Reactivity: Human

Applications: This ELISA kit is used for quantitative measurement of Adalimumab in human serum and plasma

Features & Benefits: • Easy, convenient, sensitive and time-saving method to measure the level of Adalimumab in human serum and plasma. • Detection Range: 30 - 1000 ng/ml • Sensitivity: 10 ng/ml • Assay Precision: Intra-Assay: CV < 15%; Inter-Assay: CV < 15% (CV (%) = SD/mean X 100) • Cross Reactivity: No significant cross-reactivity or interference with other proteins present in native human serum or other therapeutic immunoglobulins. • Recovery rate: 85 – 115% with normal human serum samples with known concentrations