Biovision
Anti-MUC1 recMAb™ Antibody
- SKU:
- 26-A2191
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 100 µg
- Storage Condition:
- -20ºC
- Shipping Condition:
- Gel Pack
- Shelf Life:
- 12 months
Description
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including the lung, breast stomach, and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
Antibody Target: MUC1
Target Alternative Name: EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC
Tag Line: Recombinant rabbit monoclonal antibody to detect the expression of MUC1 in human samples
Category: Primary antibody
Host: Rabbit
Antibody Type: Monoclonal
Isotype: IgG
Clone#: MUC1/2278R
Species Reactivities: Human
Immunogen Sequence: Recombinant full-length human MUC1 protein
Accession #: P15941
Gene Id: 4582
Appearance: Colorless liquid
Form: Liquid
Concentration: 1 mg/ml
Formulation: In 10 mM PBS
Purification: Protein A/G purified
Application: Immunohistochemistry (IHC)
Positive Control: N/A
Application And Usages: IHC (1-2 µg/ml)
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE