Biovision
Anti-RB1 recMAb™ Antibody
- SKU:
- 26-A2199
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 100 µg
- Storage Condition:
- -20ºC
- Shipping Condition:
- Gel Pack
- Shelf Life:
- 12 months
Description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Antibody Target: RB1
Target Alternative Name: RB, pRb, OSRC, pp110, p105-Rb, PPP1R130, p110-RB1
Tag Line: Recombinant rabbit monoclonal antibody to detect the expression of RB1 in human and mouse samples
Category: Primary antibody
Host: Rabbit
Antibody Type: Monoclonal
Isotype: IgG
Clone#: RB1/2313R
Species Reactivities: Mouse,Human
Immunogen Sequence: Recombinant human full-length RB1 protein
Accession #: P06400
Gene Id: 5925
Appearance: Colorless liquid
Form: Liquid
Concentration: 1 mg/ml
Formulation: In 10 mM PBS
Purification: Protein A/G purified
Application: Immunohistochemistry (IHC)
Positive Control: N/A
Application And Usages: IHC (1-2 µg/ml)
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE