Anti-WT1 recMAb™ Antibody

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting patterns, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. A study demonstrated that WT1 mRNA undergoes RNA editing in human and rat and that this process is tissue-restricted and developmentally regulated

Antibody Target: WT1

Target Alternative Name: WT1, AWT1, FWT1, GUD, NPHS4, WAGR, Wilms tumor 1, WT33, WIT-2

Tag Line: Recombinant mouse monoclonal antibody to detect WT1 expression in human, mouse and rat samples

Category: Primary antibody

Host: Mouse

Antibody Type: Monoclonal

Isotype: IgG1, kappa

Clone#: rWT1/857

Species Reactivities: Rat,Mouse,Human

Immunogen Sequence: Recombinant full-length human WT1 protein

Accession #: P19544

Gene Id: 7490

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In 10 mM PBS

Purification: Protein A/G purified

Application: Immunohistochemistry (IHC)

Positive Control: N/A

Application And Usages: IHC (1-2 µg/ml)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE