recMAb™ Anti-CXCR4 Antibody

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Antibody Target: CXCR4

Target Alternative Name: FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LAP-3, LESTR, NPY3R, NPYRL, WHIMS, HSY3RR, NPYY3R, D2S201E, CXCR4

Tag Line: Recombinant rabbit monoclonal antibody to detect the expression of CXCR4 in human samples

Category: Primary antibody

Host: Rabbit

Antibody Type: Monoclonal

Isotype: IgG

Clone#: 2F10

Species Reactivities: Human

Immunogen Sequence: Synthetic peptide derived from human CXCR4

Accession #: P61073

Gene Id: 7852

Appearance: Colorless liquid

Form: Liquid

Concentration: N/A

Formulation: In PBS, pH 7.4, 150 mM NaCl, 50% glycerol, 0.02% sodium azide

Purification: Affinity purified

Application: Immunofluorescence (IF)

Positive Control: N/A

Application And Usages: IF 1:20-1:200

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: TRUE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE