recMAb™ Anti-p53 Antibody

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants

Antibody Target: p53

Target Alternative Name: P53, BCC7, LFS1, BMFS5, TRP53, TP53

Tag Line: Recombinant rabbit monoclonal antibody to detect p53 expression in human, monkey, dog, hamster and chicken samples. The antibody does not react with mouse and rat samples

Category: Primary antibody

Host: Rabbit

Antibody Type: Monoclonal

Isotype: IgG

Clone#: TP53/2092R

Species Reactivities: Dog,Hamster,Chicken,Does not react with Mouse and Rat,Monkey,Human

Immunogen Sequence: Recombinant full-length human TP53 protein

Accession #: P04637

Gene Id: 7157

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In 10 mM PBS

Purification: Protein A purified

Application: Immunohistochemistry (IHC),Western Blotting

Positive Control: N/A

Application And Usages: WB (1-2 µg/ml), IHC (1-2 µg/ml)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: TRUE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE