EZSolution™ AZD-9291 (Osimertinib)

A 10 mM (5 mg in 1.0 ml) of the potent EGFR inhibitor AZD-9291 (Osimertinib) (Cat. No. 2674) in anhydrous DMSO.

Alternate Name/Synonyms: Mereletinib; Osimertinib; N-​[2-​[[2-​(Dimethylamino)​ethyl]​methylamino]​-​4-​methoxy-​5-​[[4-​(1-​methyl-​1H-​indol-​3-​yl)​-​2-​pyrimidinyl]​amino]​phenyl]​- 2-​propenamide

Appearance: Liquid

Appearance: A 10 mM solution in anhydrous DMSO

Appearance: 1421373-65-0

Appearance: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₃₃N₇O₂

Molecular Weight: 499.61

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A mutant-selective EGFR tyrosine kinase inhibitor

MDL Number:

PubChem CID: 71496458

SMILES: CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC

InChi: InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32)

InChi Key: DUYJMQONPNNFPI-UHFFFAOYSA-N

Category: Biochemicals