EZSolution™ Ionomycin free acid

Antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption. Ionomycin induces apoptosis in immature B cell lines and in cultured embryonic rat cortical neurons. More mature B cell lines do not undergo apoptosis, but are arrested in the G1 phase of the cell cycle.

Alternate Name/Synonyms:

Appearance: Liquid

Appearance: A solution in Ethanol (5 mg in 500 µl)

Appearance: 56092-81-0

Appearance: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₄₁H₇₂O₉

Molecular Weight: 709.02

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A calcium ionophore

MDL Number: MFCD06798385

PubChem CID: 6912226

SMILES: CC(CCC(=O)O)CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)O

InChi: InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+/m1/s1

InChi Key: PGHMRUGBZOYCAA-ADZNBVRBSA-N

Category: Biochemicals