EZSolution™ 5-Fluoroorotic acid monohydrate (5-FOA)

5-Fluoroorotic Acid (5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) decarboxylase. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5’-phosphate decarboxylase and are therefore unable to grow in 5-FOA-containing media.

Alternate Name/Synonyms: 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid hydrate

Appearance: Liquid

Appearance: In DMSO (100 mg/ml)

Appearance: 703-95-7, 207291-81-4, 220141-70-8

Appearance: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅H₃FN₂O₄.H₂O

Molecular Weight: 192.1

Cell-Permeable?: No

Purity: ≥97% by titration

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A solution (100 mg/ml) of 5-fluoroorotic acid (5-FOA) (Cat.No. 2796) in anhydrous DMSO.

MDL Number: MFCD00150658

PubChem CID: 16212749

SMILES: C1(=C(NC(=O)NC1=O)C(=O)O)F.O

InChi: InChI=1S/C5H3FN2O4.H2O/c6-1-2(4(10)11)7-5(12)8-3(1)9;/h(H,10,11)(H2,7,8,9,12);1H2

InChi Key: LODRRYMGPWQCTR-UHFFFAOYSA-N

Category: Biochemicals