EZSolution™ RG7388

A 10 mM (1 mg in 162 μl) solution of the p53-MDM2 interaction inhibitor RG7388 (Cat. No. 2577) in anhydrous DMSO.

Alternate Name/Synonyms: 4-[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoic acid

Appearance: Liquid

Appearance: A 10 mM solution in DMSO

Appearance: 1229705-06-9

Appearance: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₁H₂₉Cl₂F₂N₃O₄

Molecular Weight: 616.5

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective inhibitor of p53-MDM2 interaction.

MDL Number: N/A

PubChem CID: 53358942

SMILES: CC(C)(C)CC1C(C(C(N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)F

InChi: InChI=1S/C31H29Cl2F2N3O4/c1-30(2,3)14-24-31(15-36,19-10-9-17(32)13-21(19)34)25(18-6-5-7-20(33)26(18)35)27(38-24)28(39)37-22-11-8-16(29(40)41)12-23(22)42-4/h5-13,24-25,27,38H,14H2,1-4H3,(H,37,39)(H,40,41)/t24-,25-,27+,31-/m0/s1

InChi Key: TVTXCJFHQKSQQM-LJQIRTBHSA-N

Category: Biochemicals