StemBoost™ Reprogramming Cocktail, VCRFBI, Sterile-Filtered (100X)

StemBoost™ Reprogramming Cocktail, VCRFBI (100X), is a convenient, sterile-filtered cocktail solution (100X, in DMSO) for the generation of human neuronal cells from adult astrocytes. The cocktail contains the following five small molecules: CHIR99021 (Cat. No. 1677), a GSK-3β inhibitor, 300 μM; RepSox (Cat. No. 1894), a TGFβ inhibitor, 0.1 mM; Forskolin (Cat. No. 1531), a cAMP activator, 1.0 mM; I-BET151 (Cat. No. 2220), a BET bromodomain inhibitor, 200 μM; ISX9 (Cat. No. 2563), a neurogenic differentiation inducer, 1 mM. Also provided separately is a sterile-filtered solution (100X, in DI water) of the HDAC inhibitor Valproic Acid Sodium Salt (Cat. No. 1647), (50 mM).

Alternate Name/Synonyms: VCRFBI cocktail

Appearance: Liquid

Appearance: See under individual components

Appearance: See under individual components

Appearance: No

Peptide sequence: N/A

Salt Form: No

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Cell-Permeable?: True

Purity: See under individual components

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A reprogramming cocktail

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PubChem CID: N/A

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Category: Biochemicals