Human CellExp™ BCMA / TNFRSF17, Fc Tag, Cynomolgus / Rhesus macaque Recombinant

Biomolecule/Target: TNFRSF17

Synonyms: TNFRSF17, CD269, BCM, BCMA

Alternates names: TNFRSF17, CD269, BCM, BCMA

Taglines: A member of the TNF receptor superfamily

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 102145399

NCBI Gene Symbol: TNFRSF17

Gene Source: Cynomolgus/Rhesus macaque

Accession #: G7Q0I4

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGE #: > 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: Immobilized Human BAFF, His Tag at 5 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque BCMA, Fc Tag with a linear range of 0.05-2 ng/ml

Results: N/A

Binding Capacity: Immobilized Human BAFF, His Tag at 5 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque BCMA, Fc Tag with a linear range of 0.05-2 ng/ml

Unit Definition: N/A

Molecular Weight: 32.1 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally trehalose is added as protectant before lyophilization.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Background Information: Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans