Human CellExp™ CD155, IgG2a Fc Tag, Mouse Recombinant

Biomolecule/Target: CD155

Synonyms: PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5

Alternates names: PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5

Taglines: Establishes intercellular adherens junctions between epithelial cells

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 52118

NCBI Gene Symbol: PVR

Gene Source: Mouse

Accession #: Q91WP1

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: > 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: N/A

Results: N/A

Binding Capacity: Immobilized Mouse TIGIT, His Tag at 10 μg/mL (100 μL/well) can bind Mouse CD155, mouse IgG2a Fc tag with a linear range of 0.039-1.25 μg/mL mL.

Unit Definition: N/A

Molecular Weight: 61.8 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally trehalose is added as protectant before lyophilization.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 µg/ml.

Background Information: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans