Human CellExp™ CD27 / TNFRSF7, Human recombinant

Biomolecule/Target: CD27

Synonyms: CD27, TNFRSF7, S152, S152, LPFS2, T14, Tp55

Alternates names: CD27, TNFRSF7, S152, S152, LPFS2, T14, Tp55

Taglines: Member of Tumor necrosis factor receptor superfamily, play a role in survival of activated T-cells and in apoptosis through association with SIVA1.

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 939

NCBI Gene Symbol: CD27

Gene Source: Human

Accession #: NP_001233

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: >95%

Assay: SDS-PAGE

Purity: >95%

Assay #2: N/A

Endotoxin Level: < 1 EU/μg

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein is fused with a Fc tag at C-terminus and has a calculated MW of 20 kDa.

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized

Reconstitution Instructions: Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml

Background Information: Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans