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- Human CellExp™ CD3 epsilon (His-tag) & CD3 delta Heterodimer
Biovision
Human CellExp™ CD3 epsilon (His-tag) & CD3 delta Heterodimer
- SKU:
- 26-P1655
- UPC:
- MPN:
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: N/A
Synonyms: Human CellExp™ CD3 delta/epsilon,CD3E & CD3D,Human CellExp™ CD3 epsilon (His-tag) - CD3 delta Heterodimer,Human CellExp™ CD3 epsilon-CD3 delta Heterodimer,CD3 d/e,CD3 delta/epsilon,Human CellExp™ CD3 epsilon (His-tag) CD3 delta Heterodimer,CD3 delta & CD3 epsilon,CD3 epsilon (His-tag) - CD3 delta Heterodimer
Alternates names: Human CellExp™ CD3 delta/epsilon,CD3E & CD3D,Human CellExp™ CD3 epsilon (His-tag) - CD3 delta Heterodimer,Human CellExp™ CD3 epsilon-CD3 delta Heterodimer,CD3 d/e,CD3 delta/epsilon,Human CellExp™ CD3 epsilon (His-tag) CD3 delta Heterodimer,CD3 delta & CD3 epsilon,CD3 epsilon (His-tag) - CD3 delta Heterodimer
Taglines: CD3 epsilon (his-tag) and CD3 delta heterodimer important in coupling antigen recognition
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 916, 915
NCBI Gene Symbol: CD3E, CD3D
Gene Source: Human
Accession #: P07766, P04234
Recombinant: TRUE
Source: HEK 293 cells
Purity by SDS-PAGE #: ≥ 95% by SDS-PAGE
Assay: N/A
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: The calculated MW is 16 kDa (CD3E) and 13 kDa (CD3D)
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Lyophilized
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Reconstitute in sterile PBS (pH 7.4).
Background Information: T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3E, CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta, and gamma/delta heterodimers, form the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Since CD3 is required for T-Cell activation, drugs and therapeutics targeting CD3 are being researched for diseases like Type 1 diabetes and other autoimmune diseases. For example, Muromonab-CD3, a monoclonal antibody targeting the CD3 receptor, is an immunosuppressant drug to reduce acute rejection in patients with organ transplants.
Amino acid sequence: Human CD3E (Asp 23 - Asp 126) (6x His-tag at C-Terminal) and CD3D (Phe 22 - Ala 105, no His-tag)
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
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