Biovision
Human CellExp™ PSMA / FOLH1, C-His Tag, human recombinant
- SKU:
- 26-P1304
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: PSMA
Synonyms: Prostatespecific membrane antigen; Glutamate carboxypeptidase 2; PSMA; PSM; mGCP; GCPII; FGCP; NAALADase I; cell growth-inhibiting gene 27 protein; Folate hydrolase 1; Folylpoly gamma glutamate carboxypeptidase; glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N-acetylated-alpha-linked acidic dipeptidase I; Pteroylpoly-gamma-glutamate carboxypeptidase
Alternates names: Prostatespecific membrane antigen; Glutamate carboxypeptidase 2; PSMA; PSM; mGCP; GCPII; FGCP; NAALADase I; cell growth-inhibiting gene 27 protein; Folate hydrolase 1; Folylpoly gamma glutamate carboxypeptidase; glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N-acetylated-alpha-linked acidic dipeptidase I; Pteroylpoly-gamma-glutamate carboxypeptidase
Taglines: Extracellular Domain of PSMA fused to 6x His tag at the C-terminus.
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 2346
NCBI Gene Symbol: PSMA
Gene Source: Human
Accession #: Q04609
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGE #: ≥95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: This protein is fused to 6x His tag at the C-terminus and has a calculated MW of 81 kDa. The protein migrates as ~100 kDa under reducing conditions (SDS-PAGE) due to glycosylation.
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Lyophilized from filtered PBS (pH 7.4) with Trehalose (5%)
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in PBS (pH 7.4). Do not vortex.
Background Information: Human Prostate Specific Membrane Antigen (PSMA), a tumor marker in prostate cancer encoded by FOLH1 gene, is a surface glycoprotein with high expression in prostate epithelium. PSMA expression level increases in primary and metastatic prostate cancer and the neovasculature of nonprostatic epithelial malignancies. Overexpression of PSMA is correlated with high tumor grade, non-diploid tumors, and advanced tumor stage. PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. It is also recognized as a viable target for cancer therapy.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans