Human CellExp™ GITR Ligand / TNFSF18 Fc Tag, Mouse recombinant

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SKU:
26-P1126
Availability:
Usually Shipped in 5 Working Days
Storage Temperature:
-20°C
Shipping Conditions:
Gel Pack
Shelf Life:
12 months
zł764.86 - zł2,793.80
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Description

Biomolecule/Target: Tnfsf18

Synonyms: TNFSF18, AITRL, TL6, hGITRL, GITR Ligand

Alternates names: TNFSF18, AITRL, TL6, hGITRL, GITR Ligand

Taglines: Tumor necrosis factor receptor superfamily member 18

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 240873

NCBI Gene Symbol: Tnfsf18

Gene Source: Mouse

Accession #: Q7TS55

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: > 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: Immobilized Mouse GITR, His Tag at 10μg/mL (100 μL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 μg/mL.

Results: N/A

Binding Capacity: Immobilized Mouse GITR, His Tag at 10μg/mL (100 μL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 μg/mL.

Unit Definition: N/A

Molecular Weight: 41.4 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Background Information: Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans

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