Human CellExp™ IGFBP-7, Human Recombinant

Biomolecule/Target: IGFBP7

Synonyms: Insulin-like growth factor-binding protein 7, IGFBP7, IGF-binding protein 7, IGFBP-rP1, MAC25 protein, Tumor-derived adhesion factor, TAF

Alternates names: Insulin-like growth factor-binding protein 7, IGFBP7, IGF-binding protein 7, IGFBP-rP1, MAC25 protein, Tumor-derived adhesion factor, TAF

Taglines: Plays a role in skeletal myogenesis by binding to IGF

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 3490

NCBI Gene Symbol: IGFBP7

Gene Source: Human

Accession #: Q16270

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGE #: > 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 27 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose are added as protectants before lyophilization.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Background Information: Insulin-like growth factor-binding protein 7 (IGFBP7) is also known as IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor and tumor-derived adhesion factor, which contains one Ig-like C2-type (immunoglobulin-like) domain, one IGFBP N-terminal domain and one Kazal-like domain. The major function of IGFBP7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity except for IGF-I and IGF-II.IGFBP7 also stimulates cell adhesion. Furthermore, IGFBP7 is implicated in some cancers

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans