Human CellExp™ VSIG4, human recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- Gel pack
- Shelf Life:
- 12 months
Synonyms: V-set and immunoglobulin domain containing 4; Z39Ig; CRIg
Alternates names: V-set and immunoglobulin domain containing 4; Z39Ig; CRIg
Taglines: V-set and immunoglobulin domain-containing protein 4
Country of Animal Origin: USA
NCBI Gene ID #.: 11326
NCBI Gene Symbol: VSIG4
Gene Source: Human
Accession #: Q9Y279
Source: HEK 293 cells
Purity by SDS-PAGE #: ≥ 98%
Assay #2: N/A
Endotoxin Level: < 0.06 EU/mg
Activity (Specifications/test method): N/A
Biological activity: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 68 kDa
Physical form description: Lyophilized from 0.2μm-filtered solution in PBS.
Reconstitution Instructions: Reconstitute in 1X PBS to the desired protein concentration.
Background Information: VSIG4 (V-set and immunoglobulin domain containing 4), as known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans