Human CellExp™ IL-7 R alpha / CD127, IgG2a Fc Tag, Human Recombinant

Biomolecule/Target: IL7R

Synonyms: IL7Ra, CD127

Alternates names: IL7Ra, CD127

Taglines: Receptor for interleukin-7

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 3575

NCBI Gene Symbol: IL7R

Gene Source: Human

Accession #: P16871

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: > 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: N/A

Results: N/A

Binding Capacity: Immobilized Human IL-7, Tag Free at 2 μg/mL (100 μL/well) can bind Human IL-7 R alpha, mouse IgG2a Fc tag with a linear range of 4-31 ng/mL

Unit Definition: N/A

Molecular Weight: 52 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally trehalose is added as protectant before lyophilization.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 µg/ml.

Background Information: Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans