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Human CellExp™ PLGF / PGF, Rhesus macaque Recombinant

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SKU:
26-P1393
Availability:
Usually Shipped in 5 Working Days
Storage Temperature:
-20°C
Shipping Conditions:
Gel Pack
Shelf Life:
12 months
€253.00 - €906.00
Frequently bought together:

Description

Biomolecule/Target: N/A

Synonyms: PGF, PLGF, PlGF2, PlGF, PGFL, SHGC-10760

Alternates names: PGF, PLGF, PlGF2, PlGF, PGFL, SHGC-10760

Taglines: A key molecule in angiogenesis and vasculogenesis

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 701219

NCBI Gene Symbol: PGF

Gene Source: Rhesus macaque

Accession #: F7HB10

Recombinant: FALSE

Source: HEK 293 cells

Purity by SDS-PAGE #: >90% as determined by SDS-PAGE

Assay: N/A

Purity: N/A

Assay #2: N/A

Endotoxin Level: Less than 1.0 EU per μg by the LAL method

Activity (Specifications/test method): Immobilized Rhesus macaque VEGF R1, Mouse IgG2a Fc Tag, low endotoxin at 5 μg/mL (100 μL/well) can bind Rhesus macaque PLGF with a linear range of 2-40 ng/mL

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.3 kDa. The protein migrates as 28-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Lyophilized

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile deionized water. Do not vortex. It is recommended to store at -20°C.

Background Information: Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.

Amino acid sequence: AA Leu 19 - Arg 170

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans

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