Biovision
Human CellExp™ PVRIG, Fc Tag, Cynomolgus recombinant
- SKU:
- 26-P1423
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20ºC
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: N/A
Synonyms: C7orf15, CD112R, C7orf15MGC138295, MGC104322, MGC138297, MGC2463, Poliovirus receptor-related immunoglobulin domain-containing protein, transmembrane protein PVRIG
Alternates names: C7orf15, CD112R, C7orf15MGC138295, MGC104322, MGC138297, MGC2463, Poliovirus receptor-related immunoglobulin domain-containing protein, transmembrane protein PVRIG
Taglines: act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 102127364
NCBI Gene Symbol: PVRIG
Gene Source: Cynomolgus
Accession #: A0A2K5WVV8
Recombinant: True
Source: HEK 293 Cells
Purity by SDS-PAGE #: >95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.1 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Lyophilized powder
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Background Information: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Amino acid sequence: AA Thr 41 - Asp 171
Handling: Centrifuge the vial prior to opening.
Usage: N/A