Human CellExp™ PVRIG, Fc Tag, Cynomolgus recombinant

Biomolecule/Target: N/A

Synonyms: C7orf15, CD112R, C7orf15MGC138295, MGC104322, MGC138297, MGC2463, Poliovirus receptor-related immunoglobulin domain-containing protein, transmembrane protein PVRIG

Alternates names: C7orf15, CD112R, C7orf15MGC138295, MGC104322, MGC138297, MGC2463, Poliovirus receptor-related immunoglobulin domain-containing protein, transmembrane protein PVRIG

Taglines: act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 102127364

NCBI Gene Symbol: PVRIG

Gene Source: Cynomolgus

Accession #: A0A2K5WVV8

Recombinant: True

Source: HEK 293 Cells

Purity by SDS-PAGE #: >95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.1 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Lyophilized powder

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Background Information: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Amino acid sequence: AA Thr 41 - Asp 171

Handling: Centrifuge the vial prior to opening.

Usage: N/A