recMAb™ Anti-ATRX/RAD54 Antibody

The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Antibody Target: ATRX

Target Alternative Name: JMS, XH2, XNP, MRX52, RAD54, RAD54L, ZNF-HX, MRXHF1, SFM1, SHS, ATR2

Tag Line: Recombinant rabbit monoclonal antibody to detect the expression of ATRX/RAD54 in human samples

Category: Primary antibody

Host: Rabbit

Antibody Type: Monoclonal

Isotype: IgG

Clone#: ATRX/2900R

Species Reactivities: Human

Immunogen Sequence: Recombinant human ATRX protein

Accession #: P46100

Gene Id: 546

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In 10 mM PBS

Purification: Protein A/G purified

Application: Immunohistochemistry (IHC)

Positive Control: N/A

Application And Usages: IHC (1-2 µg/ml)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE