EZSolution™ Cobimetinib

A 10 mM (5 mg in 941 µl) of the potent MEK inhibitor Cobimetinib (Cat. No. B1689) in anhydrous DMSO.

Alternate Name/Synonyms: [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone; XL518; GDC0973; GDC-0973; XL-518

Appearance: Liquid

Appearance: A 10 mM solution in anhydrous DMSO

Appearance: 934660-93-2

Appearance: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₁F₃IN₃O₂

Molecular Weight: 531.31

Cell-Permeable?: True

Purity: ≥98%

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent and selective MEK inhibitor

MDL Number:

PubChem CID: 16222096

SMILES: C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O

InChi: InChI=1S/C21H21F3IN3O2/c22-14-6-5-13(19(18(14)24)27-16-7-4-12(25)9-15(16)23)20(29)28-10-21(30,11-28)17-3-1-2-8-26-17/h4-7,9,17,26-27,30H,1-3,8,10-11H2/t17-/m0/s1

InChi Key: BSMCAPRUBJMWDF-KRWDZBQOSA-N

Category: Biochemicals