EZSolution™ Propidium Iodide

Propidium iodide (PI) is a nuclear and chromosome counterstain commonly used to detect dead cells in a population. PI binds to double-stranded DNA, but it can only cross the plasma membrane of nonviable cells. When viewed using a fluorescence microscope with a rhodamine filter, cells that have lost membrane integrity will show red PI staining throughout the nuclei. For analysis by flow cytometry, the PI staining can be monitored in FL2 channel.

Alternate Name/Synonyms: 3,8-Diamino-5-(3-(diethyl(methyl)ammonio)propyl)-6-phenylphenanthridin-5-ium iodide

Appearance: Red solution

Appearance: 1 mg/ml in water

Appearance: 25535-16-4

Appearance: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₇H₃₄I₂N₄

Molecular Weight: 668.4

Cell-Permeable?: TRUE

Purity: ≥95% by TLC

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A nucleic acid stain

MDL Number: MFCD00011921

PubChem CID: 104981

SMILES: CC[N+](C)(CC)CCC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[I-].[I-]

InChi: InChI=1S/C27H33N4.2HI/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20;;/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3;2*1H/q+1;;/p-1

InChi Key: XJMOSONTPMZWPB-UHFFFAOYSA-M

Category: Biochemicals