Human CellExp™ ACVR2A (Active), Human Recombinant

Biomolecule/Target: N/A

Synonyms: Activin A Receptor Type 2A; ACTRII; ACVR2; ACTR-IIA; ACTRIIA

Alternates names: Activin A Receptor Type 2A; ACTRII; ACVR2; ACTR-IIA; ACTRIIA

Taglines: Activin receptor that may be associated with pregnancy disorders

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 92

NCBI Gene Symbol: N/A

Gene Source: Human

Accession #: P27037

Recombinant: True

Source: Human Cells

Purity by SDS-PAGE #: > 95% by SDS-PAGE

Assay: N/A

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per µg as determined by the LAL method

Activity (Specifications/test method): Immobilized Human INHBC-His at 0.8 μg/ml (100 μl/well) can bind Human ACVR2A-Fc-6His. The ED50 of Human ACVR2A-Fc-6His is 6.73 μg/ml

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 36 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized powder

Reconstitution Instructions: N/A

Background Information: Activin A receptor type 2A (ACVR2A) is a transmembrane serine/threonine kinase that mediates activin signaling in a cell-specific manner to elicit diverse biological responses. ACVR2A may be associated with susceptibility to preeclampsia, and an increase in maternal and fetal morbidity and mortality.

Amino acid sequence: Ala 20 to Pro 134 with C-terminal Fc & 6xHis Tag

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans