Human CellExp™ Angiotensin-Converting Enzyme 2 (ACE2), Human Recombinant

Biomolecule/Target: N/A

Synonyms: Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2

Alternates names: Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2

Taglines: Carboxypeptidase which converts angiotensin I to angiotensin 1-9

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 59272

NCBI Gene Symbol: ACE2

Gene Source: Human

Accession #: Q9BYF1

Recombinant: FALSE

Source: HEK 293 Cells

Purity by SDS-PAGE #: >95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): Immobilized Human ACE-2 at 10μg/ml (100 μl/well) can bind 2019-nCoV S Protein RBD-mFc .The ED50 of Recombinant 2019-nCoV S Protein RBD-mFc is 62 ng/ml.

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 84.63 kDa (C-terminal 6x His-tag)

Concentration: N/A

Appearance: Liquid protein

Physical form description: Liquid

Reconstitution Instructions: N/A

Background Information: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity.

Amino acid sequence: aa 18-740

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans