Human CellExp™ ANGPTL7 / CDT6, Human Recombinant

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SKU:
26-P1169
Availability:
Usually Shipped in 5 Working Days
Storage Temperature:
-20°C
Shipping Conditions:
Gel Pack
Shelf Life:
12 months
€204.00 - €758.00
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Description

Biomolecule/Target: ANGPTL7

Synonyms: Angiopoietin-related protein 7, ANGPTL7, CDT6, Angiopoietin-like factor, Angiopoietin-like protein 7, Cornea-derived transcript 6 protein

Alternates names: Angiopoietin-related protein 7, ANGPTL7, CDT6, Angiopoietin-like factor, Angiopoietin-like protein 7, Cornea-derived transcript 6 protein

Taglines: Growth factor that enhance the expansion and engraftment of hematopoietic stem cells

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 10218

NCBI Gene Symbol: ANGPTL7

Gene Source: Human

Accession #: O43827

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGE #: > 85%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Human LILRB4, Fc Tag with a linear range of 0.031-0.5 μg/mL Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Human LILRB2, Fc Tag with a linear range of 0.031-2 μg/mL Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Human LILRA3, Fc Tag with a linear range of 0.016-1 μg/mL

Results: N/A

Binding Capacity: Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Human LILRB4, Fc Tag with a linear range of 0.031-0.5 μg/mL Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Human LILRB2, Fc Tag with a linear range of 0.031-2 μg/mL Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Human LILRA3, Fc Tag with a linear range of 0.016-1 μg/mL

Unit Definition: N/A

Molecular Weight: 39 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration up to 0.2 mg/ml.

Background Information: Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans

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