Human CellExp™ Beta 2 Microglobulin

Biomolecule/Target: N/A

Synonyms: B2M

Alternates names: B2M

Taglines: A component of the class I major histocompatibility complex

Taglines: USA

Country of Animal Origin: N/A

NCBI Gene ID #.: 567

NCBI Gene Symbol: N/A

Gene Source: Human

Accession #: P61769

Recombinant: TRUE

Source: HEK293 cells

Purity by SDS-PAGE #: ≥ 97% by SDSPAGE

Assay: N/A

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 0.1 EU/μg of the protein as determined by LAL method

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: The protein migrates as a ~12-13 kDa band in SDS-PAGE

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized protein

Reconstitution Instructions: Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.

Background Information: Beta 2 Microglobulin is a component of the class I major histocompatibility complex (MHC). It presents the antigenic peptides to the immune system. It is present in small amounts in serum, csf, and urine of normal people and to a much greater degree in the urine and plasma of patients with tubular proteinaemia, renal failure or kidney transplants. The levels of Beta 2 Microglobulin are increased in multiple myeloma. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions.

Amino acid sequence: aa Ile21-Met119

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans