Human CellExp™ Cystatin C, Human Recombinant

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SKU:
26-4878
Availability:
Usually Shipped in 5 Working Days
Storage Temperature:
-20°C
Shipping Conditions:
Blue ice
Shelf Life:
12 months
€278.00 - €906.00
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Description

Biomolecule/Target: N/A

Synonyms: Human Recombinant Cystatin C

Alternates names: Cystatin-3, Gamma-trace neuroendocrine basic polypeptide, Post-gamma-globulin

Taglines: A biomarker of kidney function

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 1472

NCBI Gene Symbol: CST4

Gene Source: Human

Accession #: P01036

Recombinant: Yes

Source: Human 293 cells

Purity by SDS-PAGE #: ≥95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: <0.1 ng/μg

Activity (Specifications/test method): N/A

Biological activity: The inhibitory function of Cystatin C on papin’s protease activity was measured by a colorimetric assay using L-BAPA as substrate. IC50 value was measured at 5 to 20 µg/mL (0.3 to 1.5 µM) with a range of 1.56 µg/mL to 50 µg/mL Cystatin C in presence of 0.55 µM papain and 0.44 µM L-BAPA.

Results: Typically 0.3 to 1.5 µM IC50.

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 12-13 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized in PBS

Reconstitution Instructions: Reconstitute in sterile PBS.

Background Information: Xeno-free Cystatin C HuXp (Cys-C) is expressed in human 293 cells as a monomer with an apparent molecular mass of 12 to 13 kDa. Native Cys-C in human urine is found in two different forms: one with pI 9.2 and the other with pI 7.8 by elimination of small basic peptides or amino acids from the N-terminal end of protein. Cystatin C has been studied for its role in predicting new onset or deteriorating cardiovascular disease. This cytokine is produced in a serum-free, chemically defined media.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans

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