Biovision
Human CellExp™ Dermatopontin, Human Recombinant
- SKU:
- 26-P1319
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 10 µg
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: DPT
Synonyms: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP and DPT
Alternates names: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP and DPT
Taglines: Tyrosine-rich acidic matrix protein that communicate between the dermal fibroblast cell surface and its extracellular matrix environment
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 1805
NCBI Gene Symbol: DPT
Gene Source: Human
Accession #: Q07507
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGE #: >95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: N/A
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4
Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 100 µg/ml.
Background Information: Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.
Amino acid sequence: QYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPQGQVIVAVRSIFSKKEGSDRQWNYACMPTPQS LGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTIE YPGHYGEEMDMISYNYDYYIRGATTTFSAVERDRQWKFIMCRMTEYDCEFANVVDDIEGRMDEPK SCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVE VHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQV YTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVD KSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used on humans