Biovision
Human CellExp™ DLL4, Mouse Recombinant
- SKU:
- 26-P1163
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: Dll4
Synonyms: Delta-like Protein 4, Delta 4
Alternates names: Delta-like Protein 4, Delta 4
Taglines: Activates the Notch-1 and Notch-2 receptors
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 54485
NCBI Gene Symbol: Dll4
Gene Source: Mouse
Accession #: Q9JI71
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGE #: > 90%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/μg
Activity (Specifications/test method): Measured by inhibition of adipogenesis of 3T3L-1 cells
Biological activity: Inhibits adipogenesis of 3T3L-1 cells
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 95 kDa
Concentration: N/A
Appearance: Liquid
Physical form description: 0.2 μm-filtered solution in PBS
Reconstitution Instructions: N/A
Background Information: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans