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Human CellExp™ DLL4, Mouse Recombinant

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SKU:
26-P1163
Availability:
Usually Shipped in 5 Working Days
Storage Temperature:
-20°C
Shipping Conditions:
Gel Pack
Shelf Life:
12 months
€228.00 - €758.00
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Description

Biomolecule/Target: Dll4

Synonyms: Delta-like Protein 4, Delta 4

Alternates names: Delta-like Protein 4, Delta 4

Taglines: Activates the Notch-1 and Notch-2 receptors

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 54485

NCBI Gene Symbol: Dll4

Gene Source: Mouse

Accession #: Q9JI71

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: > 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): Measured by inhibition of adipogenesis of 3T3L-1 cells

Biological activity: Inhibits adipogenesis of 3T3L-1 cells

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 95 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: 0.2 μm-filtered solution in PBS

Reconstitution Instructions: N/A

Background Information: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans

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